The usefulness of serum transferrin receptor for discriminating iron deficiency without anemia in children.

نویسندگان

  • Maria Angeles Vázquez Lopez
  • Amparo Carracedo
  • Francisco Lendinez
  • Francisco Javier Muñoz
  • Juan López
  • Antonio Muñoz
چکیده

We determined serum transferrin receptor (sTfR), serum erythropoietin and hematologic and biochemical iron parameters in 251 healthy children. The levels of sTfR were significantly higher in children with storage iron deficiency but had a poor sensivity for recognizing iron deficiency without anemia. When ferritin values cannot accurately demonstrate the iron deficiency in children, the sTfR/ferritin ratio or sTfR-log ferritin is recommended to discriminate iron deficiency in the absence of anemia.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The prevalence of iron deficiency anemia in 1-5 years old children referring to Kerman medical care and health centers in 1998

Iron deficiency anemia(IDA) is one of the most common nutritional problems in the world.children under 5 years old are considerd as the high risk group consisting a high proportion of IDA patients.in this group,due to the specific conditions,the complication of anemia may lead to serious consequences.this study was designed to determine the prevalence of IDA in 1-5 years old children.A total of...

متن کامل

The usefulness of soluble transferrin receptor (sTfR) in differentiating anemia occurring in young children.

We evaluated the usefulness of soluble transferrin receptor (sTfR) and of the sTfR/log ferritin index(sTfR/logF) in the differentiation of anemia in young children. 96 children, aged 6-36 months, were examined.From these, four groups were distinguished: 1 - (IDA): 33 children with anemia due to iron deficiency; 2 -(IA): 19 children with infectious anemia without iron deficiency; 3 - (IA + ID): ...

متن کامل

Is Childhood Obesity Associated with Iron Deficiency Anemia?

Background: The prevalence of obesity is increasing and many countries are struggling with its high rate and serious complications. As a result of distinct diet in obese children, they may be susceptible to nutritional deficiencies in particular, iron deficiency. This study aimed to examine the relationship between obesity and iron indices. Methods: In this cross-sectional study, 206 element...

متن کامل

Assessment of Mean Corpuscular Volume as a Surrogate Marker for Detecting Early Iron Deficiency among School Children

Background: The aim of the present study was to assess the mean corpuscular volume (MCV) as a surrogate marker for detecting early iron deficiency prior to definitive investigation and treatment. Materials and Methods: This study was done on one hundred students in Swada Preparatory School – Sharkia Governorate from 2010 to 2011. They were subdivided into three groups: Group (A): comprised of...

متن کامل

Discriminating between iron deficiency anemia and anemia of chronic disease using traditional indices of iron status vs transferrin receptor concentration.

We compared the ability of soluble serum transferrin receptor (TfR) concentration, quantified using the R&D Systems (Minneapolis, MN) enzyme-linked immunosorbent TfR assay, with other, more traditional indicators of iron status (total iron binding capacity [TIBC], mean corpuscular volume [MCV], percent transferrin saturation [%TS], RBC distribution width [RDW], and serum iron concentration [SIC...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Haematologica

دوره 91 2  شماره 

صفحات  -

تاریخ انتشار 2006